Extraction of caffeine and catechins using microwave-assisted and ultrasonic extraction from green tea leaves: an optimization study by the IV-optimal design

In this research, optimal conditions for extraction of caffeine and polyphenols were established from Iranian green tea leaves. In the first step, caffeine was extracted with efficacy about 86% versed to 4.5% of EGC + EGCG. The EGCG + EGC was extracted from partially decaffeinated green tea leaves through microwave-assisted extraction (MAE) and ultrasound-assisted extraction (USE) with efficiency levels of 95 and 85%, respectively. The best results for the MAE process were obtained with 7.8 min and three number of extraction cycles and for the USE process were as followed: time 57 min, temperature 65 °C, and the number of extraction cycles 3. The total phenol content values at the best conditions of MAE and the USE processes were 125 ± 5 and 96 ± 6 mg gallic acid/g DW. The 50% inhibition (IC₅₀) on 1,1-diphenyl-2-picrylhydrazyl (DPPH) were 56 and 66 mg/g of phenol for the MAE and USE processes.     

Application of LS-SVM strategy to estimate H2S loading capacity in different ionic liquids and alkanolamines

Favorable properties of aqueous solutions are improved with the addition of different materials for separation of hydrogen sulfide (H₂S). Also, equilibrium data and available equations for solubility estimation of this gas are only valid for specific solutions and limited ranges of temperature and pressure. In this regard, a machine learning model based on Support vector machine (SVM) algorithm is proposed and developed with mixtures containing different amines and ionic liquids to predict H₂S solubility over wide ranges of temperature (298–434.5 K), pressure (13–9319 kPa), overall mass concentration (3.82–100%) and mixture's apparent molecular weight (18.39–556.17 g/mol). The accuracy of the performance of this network was evaluated by regression analysis on calculated and experimental data, which had not been used in network training.     

Simple size-controlled fabrication of Zn2SnO4 nanostructures and study of their behavior in dye sensitized solar cells

Zn₂SnO₄ nanostructures were obtained via facile and rapid co-precipitation approach in presence of amines with different long chain as a novel basic and capping agents. The effect of different amines such as NH₃, ethylenediamine, triethylenetetramine, tetraethylenepentamine on the size of Zn₂SnO₄ nanostructures were investigated. The results demonstrated that applying the appropriate amount of organic amine could be effective in particle size control. The obtained nanostructure products were specified by powder X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectra, scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX) and ultraviolet–visible (UV–vis) spectroscopy. Dye sensitized solar cells (DSSC) were created by the constructed electrodes as working electrode and then were studied by current density–voltage (J–V) curve. It was found that incorporating of TiO₂ nanoparticles to optimized Zn₂SnO₄ nanostructures has significant role on the constructed DSSCs photovoltaic properties.     

Efficient repairing effect of PEG based tri-block copolymer on mechanically damaged PC12 cells and isolated spinal cord

Membrane sealing effects of polymersomes made of tri-block copolymer, PEG-co-FA/SC-co-PEG, (PFSP) were studied on isolated spinal cord strips, PC12 cell lines and artificial bilayer following mechanical impact implemented by aneurism clip, sonication and electric shock, respectively. The homogeneity and size of PFSP, membrane permeability and cell viability were assessed by dynamic light scattering, LDH release and MTT assays. According to the results, the biocompatible, physico-chemical, size, surface charge and amphipathic nature of PFSP polymersome makes it an ideal macromolecule to rapidly reseal damaged membranes of cells in injured spinal cord as well as in culture medium. Compound action potentials recorded from intentionally damaged spinal cord strips incubated with PFSP showed restoration of neural excitability by 82.24 % and conduction velocity by 96.72 % after 5 min that monitored in real time. Thus, they triggered efficient instant and sustained sealing of membrane and reactivation of temporarily inactivated axons. Treatment of ultrasonically damaged PC12 cells by PFSP caused efficient cell membrane repair and led to their increased viability. The optimum effects of PFSP on stabilization and impermeabilizing of the lipid bilayer occurred at the same concentrations applied to the damaged cells and spinal cord fibers and was approved by restoration of membrane conductance and calcein release manifested by NanoDrop technique. The unique physico-chemical characteristics of novel polymersomes introduced here, make them capable to reorganize membrane lipid molecules, reseal the breaches and restore the hydrophobic insulation in spinal cord damaged cells. Thus, they might be considered in the clinical treatment of SCI at early stages.     

Narrow‐band interference suppression in wavelet packets based multicarrier multicode CDMA overlay system

The wavelet packets based multicarrier (MC) multicode (MCD) code‐division multiple‐access (CDMA) transceiver consists of the MCD part, which ensures the transmission for high speed and flexible data rate; the MC part contributing to robustness to frequency‐selective fading and flexibility for handling multiple data rates; and wavelet packets (WPs) modulation technique, which contributes to the mitigation of the interference problems. As WPs have lower sidelobes compared with sinusoidal carriers, this system is very effective in reducing the problem of inter‐carrier interference. Of course, like any CDMA system, the system can suppress a given amount of interference. This paper considers an interference suppression scheme which will enhance the performance of the system. The receiver employs suppression filters to mitigate the effect of narrow‐band jammer interference. The framework for the system and the performance evaluation are presented in terms of the bit error rate and the outage probability over a Nakagami fading channel. Also, we investigate how the performance is influenced by various parameters, such as the number of taps of the suppression filter and the ratio of narrow‐band interference bandwidth to the spread‐spectrum bandwidth. Finally, the performance of the system is compared with the performance of sinusoidal based MC/MCD‐CDMA system denoted Sin‐MC/MCD‐CDMA. Copyright © 2012 John Wiley & Sons, Ltd.     

Determination of trace amount of silver in water samples by flame atomic absorption after preconcentration by ZnO nano sorbent

A simple and fast method based on solid phase extraction (SPE) applying zinc oxide (ZnO) nanoparticles and atomic absorption spectrometry (AAS) was developed for the trace amount determination of silver (Ag) in aqueous samples. The method linearity was in the range of 14 to 700 ng mL^?1. The extraction efficiency of Ag was greater than 98% and limit of detection (LOD) was 4.2 ng mL^?1. The preconcentration factor was 200 and the relative standard deviation (RSD%) of the method was 3.7% (n = 6).     

Polyester composite water uptake and organic contaminant release affected by carbon nanofiber reinforcements

The incorporation of carbon nanofiber (CNF) into glass fiber (GF) composites is a potential route to extend polymer composite service‐life and enhance mechanical properties. Under nonstatic conditions, only limited information concerning water uptake and contaminant release properties of nanocomposite materials is currently available. Polyester composites containing GF and oxidized CNF were immersed in water for 30 days under nominal pressure at 23 °C, below the polymer's glass‐transition temperature. Water was analyzed and changed every three days to simulate water chemistry regeneration similar to exposures in flowing systems. Composites with oxidized CNF had greater water sorption capacity and leaching rates than CNF‐free composites. The total mass of organic contaminant released correlated with the amount of water sorbed by each composite (r² = 0.91), although CNF dispersion was found to vary greatly within composites. The greatest and least contaminant release rates were found for the polyester‐CNF and the polyester‐GF composites, respectively. While volatile aromatic resin solvents and stabilizer compounds were detected, their concentrations declined over the 30 day exposure period. We hypothesize that the hydrophilic nature of the oxidized CNF increased the water sorption capacity of the polyester composites. Additional studies are warranted that examine the impact of this phenomenon on composite mechanical and long‐term durability properties. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 43724.     

Thermosensitive folic acid-targeted poly (ethylene-<Emphasis Type="Italic">co</Emphasis>-vinyl alcohol) hemisuccinate polymeric nanoparticles for delivery of epirubicin to breast cancer cells

A novel thermosensitive folic acid (FA)-targeted succinylated poly (ethylene-co-vinyl alcohol) (EVOH) (EVOHS-FA) nanocarrier was synthesized for the specific delivery of epirubicin (EPI) to MCF-7 breast cancer cell line. Three different ratios of synthesized EVOH-Suc were reacted with FA. The structure of the desired products (EVOHS₄₀-FA, EVOHS₆₀-FA and EVOHS₈₀-FA) was confirmed by ¹H NMR and FTIR techniques. Nanoparticles were obtained by nano-precipitation procedure using DMSO/H₂O as solvent/anti-solvent. The particle size, zeta potential, entrapment efficacy and in vitro release profile of the final formulations in different temperatures were measured. The optimized nanoparticles had the particle size of 214 ± 8.5 nm, zeta potential of ?29.6 mV, PDI of 0.198 ± 0.04, and a high encapsulation efficiency that released the drug efficiently within 450 h at the temperature of 40 °C compared to 37 °C. The morphology of nanoparticles was studied by scanning electron microscopy. The in vitro cytotoxicity was evaluated using the MTT assay on MCF-7 cell lines in response to temperatures of 37 and 40 °C. The MTT assay indicated that the targeted nanoparticles carrying EPI were significantly more cytotoxic than the non-targeted nanoparticles and the free drug at 40 °C.